Correlation of hs-CRP Levels and Total Protein In Patients With Type 2 Diabetes Mellitus At Dr. Bratanata Hospital Jambi City

Annisa Raehannur Zahra; James P. Simanjuntak; Witi Karwiti

doi:10.35910/icohpj.v5i0.1040

Annisa Raehannur Zahra Medical Laboratory Technology Department, Health Polytechnic of Jambi, Indonesia
James P. Simanjuntak Medical Laboratory Technology Department, Health Polytechnic of Jambi, Indonesia
Witi Karwiti Medical Laboratory Technology Department, Health Polytechnic of Jambi, Indonesia

DOI: https://doi.org/10.35910/icohpj.v5i0.1040

Keywords: Diabetes mellitus, Total protein, hs-CRP, Inflammation

Abstract

Background: Type 2 Diabetes Mellitus (DM) is a chronic disease characterized by hyperglycemia and mild systemic inflammation. High-sensitivity C-Reactive Protein (hs-CRP) is an inflammatory marker elevated in type 2 DM, while total protein levels reflect the nutritional and inflammatory status of the body. The correlation between hs-CRP and total protein may provide insight into the inflammatory and metabolic status of type 2 DM patients.

Methods: This descriptive-analytic study used a cross-sectional design and was conducted at Dr. Bratanata Hospital, Jambi City. The sample consisted of T2DM patients selected through purposive sampling based on inclusion and exclusion criteria. hs-CRP levels were measured using a Wondfo Meter, and total protein was analyzed using an Autolyser BT 3500. Statistical tests were conducted to determine the relationship between the variables.

Results: The average hs-CRP level was 4.25 mg/L and the total protein level was 7.40 g/dL. A weak negative correlation was found between hs-CRP and total protein levels, which was statistically significant (p = 0.023).

Conclusion: There is a significant correlation between hs-CRP and total protein levels in type 2 DM patients. Increased hs-CRP tends to be followed by a decrease in total protein levels, although the correlation is weak. Measurement of hs-CRP and total protein can serve as early indicators of inflammatory and metabolic status in type 2 DM patients.