Correlation of HS-CRP Levels and Total Cholesterol in Patients with Type 2 Diabetes Mellitus at Dr. Bratanata Hospital Jambi City

Fadhillah Nurul Amalia; James P. Simanjuntak; Sholeha Rezekiyah

doi:10.35910/icohpj.v5i0.1037

Fadhillah Nurul Amalia Medical Laboratory Technology Department, Health Polytechnic of Jambi, Indonesia
James P. Simanjuntak Medical Laboratory Technology Department, Health Polytechnic of Jambi, Indonesia
Sholeha Rezekiyah Medical Laboratory Technology Department, Health Polytechnic of Jambi, Indonesia

DOI: https://doi.org/10.35910/icohpj.v5i0.1037

Keywords: Diabetes mellitus, Total cholesterol, hs-CRP, Inflammation

Abstract

Background: Type 2 Diabetes Mellitus (T2DM) is associated with disturbances in glucose and lipid metabolism that can trigger systemic inflammation. High-sensitivity C-reactive protein (hs-CRP) is a biomarker commonly used to predict cardiovascular risk, especially when assessed alongside total cholesterol levels. This study aims to investigate the relationship between high-sensitivity C-reactive protein (hs-CRP) levels and total cholesterol in individuals with type 2 diabetes mellitus.

Method: This descriptive-analytic study used a cross-sectional design and was conducted at Dr. Bratanata Hospital, Jambi City. The sample consisted of T2DM patients selected through purposive sampling based on inclusion and exclusion criteria. hs-CRP levels were measured using a Wondfo Meter, and total cholesterol was analyzed using an Autolyser BT 3500. Statistical tests were conducted to determine the relationship between the variables.

Result: The average hs-CRP level was 4.25 mg/L, and the average total cholesterol was 218 mg/dL. There was no significant correlation between hs-CRP and total cholesterol levels (p > 0.05). The regression plot suggested a possible negative trend, the correlation was weak and not statistically significant.

Conclusion: There is no significant correlation between hs-CRP and total cholesterol levels in T2DM patients at Dr. Bratanata Hospital, Jambi City.